Description
March 3, 2026
Cancer Stress Protein Helps Tumors Hide from Immunity – NYU Langone Health
What Is the Most Important Blood Test for Multiple Myeloma?
Hosted on Ausha. See ausha.co/privacy-policy for more information.
Transcription
- Nick Lanyi
The CAP sends HHS its recommendations on AI use in laboratory medicine. A new study identifies a protein that shields tumors from immune response. And we hear from a CAP member who is one of our most active advocates on policy issues that matter to pathologists. These stories and more coming up next. This is Path News Network Daily Edition from the College of American Pathologists. I'm Nick Lanyi. It's Tuesday, March 3rd. On the AI front, the CAP submitted comments to the Department of Health and Human Services last week recommending reliable, safe, and effective ways to use AI to enhance clinical care while preserving high standards in laboratory medicine. The CAP recommendations focused on three areas, preserving the FDA's role in reviewing AI-enabled medical devices and software. applying lessons from the CAP's laboratory accreditation experience to AI oversight and quality, and ensuring that pathologists lead in selecting, validating, and using AI systems in the laboratory. A new study by NYU Langone Health holds promise for the treatment of some cancers. Researchers found that cancer cells respond to stress by releasing the protein lipocalin-2, or LCN2, which stops cancer-killing T-cells from entering lung and pancreatic tumors. Because cancer cells are irregular, they are constantly stressed. The researchers found an antibody that blocks LCN2 and helped to shrink tumors in mice with cancer. Combining the LC2 antibody with an existing immunotherapy drug extended survival in mice with aggressive lung cancer. Treatments for multiple myeloma have advanced in recent years, extending life expectancies for those suffering from this incurable disease. A recent article in Patient Power described one of the key tests doctors use to diagnose and monitor multiple myeloma, serum protein electrophoresis, or SPEP. The SPEP detects the presence of monoclonal immunoglobin in the patient's blood serum, creating an M-spike pattern in test results. that indicates the presence of myeloma cells in the bone marrow. By monitoring SPAP tests over time, doctors gain important insights into the patient's condition and treatment response. And finally, Dr. Elizabeth Martin has been a practicing pathologist for more than 40 years, currently at Fauquier Hospital in Warrington, Virginia. She's been a member of the CAP since 1979, when she was a first-year pathology resident. And this former winner of the Association's Advocate of the Year Award is still working hard to advance the interests of pathologists. In fact, she recently continued her streak of being one of the first members to register for our House of Delegates and Pathologists Leadership Summit, which this year will be held April 25th to 28th in Washington, D.C. We asked Dr. Martin why she is so invested in the CAP's advocacy work.
- Dr. Elizabeth Martin
Pathology is a relatively small part of the House of Medicine. And we think we're very important, but if we don't speak up for ourselves, then nobody's going to be speaking up for us. And the group voice as the CAP is much stronger than my individual voice.
- Nick Lanyi
Dr. Martin has contributed to fighting Medicare payment cuts, supporting training programs, adding residency slots, and securing visas for foreign graduates. What's the priority this year on a national level?
- Dr. Elizabeth Martin
physicians, not just pathologists, all physicians are the one group which does not have an inflation adjustment built into the Medicare reimbursement. So Medicare was started, I guess, 1964 thereabouts, and inflation has gone up a lot since then. And cost of living, cost of our supplies, everything goes up every year, but we're not allowed to recoup that through inflation adjustment.
- Nick Lanyi
Do you have any advice for members participating in their first Hill Day?
- Dr. Elizabeth Martin
To not be intimidated. They're not going alone. They're going to be well educated before they go. They're unlikely to be meeting with a senator or representative. They're going to be meeting with young, very smart aides in the department. And main thing to remember is that they may know a lot more about legislation than we do, but the person going in there knows a whole lot more about pathology and And the more you can educate them about what we do and our importance for taking care of individual patients and improving health care of our communities, the better they're able to understand and the more willing they are to help us with our legislative needs.
- Nick Lanyi
Thank you, Dr. Martin, for showing up and speaking up on behalf of pathologists. That's the Daily Edition for today. For more information on today's stories, check the show notes. And look for more news like this in the CAP's Advocacy Newsletter every Tuesday and our weekly edition newsletter on Thursdays. We'll be back tomorrow at 5 a.m. Eastern for another episode of The Daily Edition. I'm Nick Lanyi. Have a wonderful day.
Description
March 3, 2026
Cancer Stress Protein Helps Tumors Hide from Immunity – NYU Langone Health
What Is the Most Important Blood Test for Multiple Myeloma?
Hosted on Ausha. See ausha.co/privacy-policy for more information.
Transcription
- Nick Lanyi
The CAP sends HHS its recommendations on AI use in laboratory medicine. A new study identifies a protein that shields tumors from immune response. And we hear from a CAP member who is one of our most active advocates on policy issues that matter to pathologists. These stories and more coming up next. This is Path News Network Daily Edition from the College of American Pathologists. I'm Nick Lanyi. It's Tuesday, March 3rd. On the AI front, the CAP submitted comments to the Department of Health and Human Services last week recommending reliable, safe, and effective ways to use AI to enhance clinical care while preserving high standards in laboratory medicine. The CAP recommendations focused on three areas, preserving the FDA's role in reviewing AI-enabled medical devices and software. applying lessons from the CAP's laboratory accreditation experience to AI oversight and quality, and ensuring that pathologists lead in selecting, validating, and using AI systems in the laboratory. A new study by NYU Langone Health holds promise for the treatment of some cancers. Researchers found that cancer cells respond to stress by releasing the protein lipocalin-2, or LCN2, which stops cancer-killing T-cells from entering lung and pancreatic tumors. Because cancer cells are irregular, they are constantly stressed. The researchers found an antibody that blocks LCN2 and helped to shrink tumors in mice with cancer. Combining the LC2 antibody with an existing immunotherapy drug extended survival in mice with aggressive lung cancer. Treatments for multiple myeloma have advanced in recent years, extending life expectancies for those suffering from this incurable disease. A recent article in Patient Power described one of the key tests doctors use to diagnose and monitor multiple myeloma, serum protein electrophoresis, or SPEP. The SPEP detects the presence of monoclonal immunoglobin in the patient's blood serum, creating an M-spike pattern in test results. that indicates the presence of myeloma cells in the bone marrow. By monitoring SPAP tests over time, doctors gain important insights into the patient's condition and treatment response. And finally, Dr. Elizabeth Martin has been a practicing pathologist for more than 40 years, currently at Fauquier Hospital in Warrington, Virginia. She's been a member of the CAP since 1979, when she was a first-year pathology resident. And this former winner of the Association's Advocate of the Year Award is still working hard to advance the interests of pathologists. In fact, she recently continued her streak of being one of the first members to register for our House of Delegates and Pathologists Leadership Summit, which this year will be held April 25th to 28th in Washington, D.C. We asked Dr. Martin why she is so invested in the CAP's advocacy work.
- Dr. Elizabeth Martin
Pathology is a relatively small part of the House of Medicine. And we think we're very important, but if we don't speak up for ourselves, then nobody's going to be speaking up for us. And the group voice as the CAP is much stronger than my individual voice.
- Nick Lanyi
Dr. Martin has contributed to fighting Medicare payment cuts, supporting training programs, adding residency slots, and securing visas for foreign graduates. What's the priority this year on a national level?
- Dr. Elizabeth Martin
physicians, not just pathologists, all physicians are the one group which does not have an inflation adjustment built into the Medicare reimbursement. So Medicare was started, I guess, 1964 thereabouts, and inflation has gone up a lot since then. And cost of living, cost of our supplies, everything goes up every year, but we're not allowed to recoup that through inflation adjustment.
- Nick Lanyi
Do you have any advice for members participating in their first Hill Day?
- Dr. Elizabeth Martin
To not be intimidated. They're not going alone. They're going to be well educated before they go. They're unlikely to be meeting with a senator or representative. They're going to be meeting with young, very smart aides in the department. And main thing to remember is that they may know a lot more about legislation than we do, but the person going in there knows a whole lot more about pathology and And the more you can educate them about what we do and our importance for taking care of individual patients and improving health care of our communities, the better they're able to understand and the more willing they are to help us with our legislative needs.
- Nick Lanyi
Thank you, Dr. Martin, for showing up and speaking up on behalf of pathologists. That's the Daily Edition for today. For more information on today's stories, check the show notes. And look for more news like this in the CAP's Advocacy Newsletter every Tuesday and our weekly edition newsletter on Thursdays. We'll be back tomorrow at 5 a.m. Eastern for another episode of The Daily Edition. I'm Nick Lanyi. Have a wonderful day.
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