- Nancy Johnson
Today, extra-chromosomal DNA in advancing diagnostics, and what data can tell us about fighting cancer, coming up on the Path News Network.
This is Path News Network Daily Edition, powered by the College of American Pathologists. I'm Nancy Johnson. It's Wednesday, September 3rd. Here are the latest headlines.
Extra-chromosomal DNA is far more common in cancer than once thought. Called ecDNA, it was detected in 17% of tumors and linked to metastasis, treatment resistance, and shorter patient survivals, a recent study in Nature reveals. Study co-author Dr. Paul Mischel explains how ecDNA may be the missing link in understanding cancer's rapid evolution. according to CAP Today. For pathologists, detection of ecDNA will be central to improving patient outcomes. Read the story in the show notes.
Do you want to learn more about structured synoptic reporting of data and the role of pathology in public health innovation? The Cancer Data Summit at CAP25 will bring together leaders across cancer care to explore how advancements and data capture and improvements in data. interoperability can drive research breakthroughs. The third annual summit will be held all day on September 12th. The link to register for CAP25 is in the show notes.
A memoir from incoming CAP president-elect Dr. Kalisha Hill. She just released her new book, "Pinnacles: Visible and Invisible," a powerful account of her journey from humble beginnings to leadership in pathology. A portion of the proceeds from the book will benefit the CAP Foundation, supporting initiatives that advance patient care and the profession. Members can order the memoir and bring copies to CAP25, where Dr. Hill will be signing in person. With honesty and insight, the story takes readers into her inner world, where she balances public perception with authenticity. Please visit the show notes for a link to purchase the book.
And finally, learn about the hidden cost of exhaustion at CAP25. Make sure you don't miss the fireside chat between Drs. Srividya Sathiyamoorthy and Dr. Aaron Auerbach. We spoke with them about why pathologists should be paying attention to their sleep. What drew each of you to the topic of sleep?
- Dr. Srividya Sathiyamoorthy
Being part of the wellness project team and also being very interested in wellness, and you know I do other programs for wellness for my hospital system, we are doing a weekly meditation session as part of the wellness effort. I realized and being part of the group that I meditate with, we have published several articles on the benefits of meditation and one of the reasons or improvements is on sleep. And there are several articles that have been published in global international journals on how sleep quality can be improved with meditation. And that's one of the reasons why I wanted to share this with my colleagues so they could take the benefit of this knowledge.
- Dr. Aaron Auerbach
And for me, I can tell you I'm drawn to sleep. Well, for one thing, it's something I've done for my entire life. But no, no, my real reason for being drawn to sleep to the topic of sleep is that before, a long, long time ago, before I was a pathologist, and I was trying to get some experience for medical school, I worked as a sleep technician, which is, you know, that field is known as a polysomnographer. And I would stay up all night, and I would hook people up to EEGs and machines, and I would follow their sleep. And then the doctor would come in the next day and interpret the findings. So I've always been very interested in the science end of sleep.
- Nancy Johnson
What's the one lesson you hope people will take away from this fireside chat at CAP25?
- Dr. Srividya Sathiyamoorthy
I would say that complete wellness means physical, mental, and spiritual. So all three aspects of our body need to work toward wellness. And since sleep has been shown such an essential part of our wellness, not only for mental wellness, but also physical wellness, a good rested body feels fresh and can work in the high pressure field of pathology. Every day we are diagnosing cancer. We're dealing with a lot of issues in the lab, managing quality reporting of testing in the lab, dealing with numerous other external and internal issues that come up every day. So it's very important for us to focus on our well-being and care of the self. And for that one of the important things is sleep. And people, I feel, do not give it enough importance and acknowledgement. And it's not only important to get the required quantity of sleep, because, you know, the glymphatic system of the brain cleanses all the toxins in the brain only in deep NREM sleep. And it takes about four hours for us to reach that during the normal sleep cycles. But meditation as a tool. can improve the quality of our sleep and help us reach those deep states of sleep, which will help us rejuvenate our brain and function better as a pathologist.
- Dr. Aaron Auerbach
And I think another message is that good sleep will lead to decreased errors. We see that pathologists have an increasing workload. And we all know that once we get fatigued, that's when we are most likely to make an error that we wouldn't have made otherwise. And good sleep is the number one way to assure that our errors are decreased.
- Nancy Johnson
This fireside chat will offer pathologists practical tools to improve their sleep quality. What are the main takeaways for busy pathologists who attend the annual meeting?
- Dr. Srividya Sathiyamoorthy
There are several suggestions that, you know, sleep specialists give us on things to do and things to avoid. to get a better quality sleep. One of the things is to avoid caffeine products after a certain time during the day. The other thing is not to engage with electronics just before sleep. So, you know, depending on when your sleep time is, for two hours before that, just stop engaging in electronics. Several people suggest things that calm our mind, like reading or... If you are a spiritual person to engage in a brief prayer just before your sleep. These are certain things that I would suggest daily meditation practice that will improve your sleep quality.
- Dr. Aaron Auerbach
And I'll just add that some good exercise during the day helps relax the body at nighttime to sleep through the night.
- Nancy Johnson
That's all for today. Be sure to watch your email inbox for more news like this in the CAP's advocacy newsletter every Tuesday and our weekly edition newsletter every Thursday. Listen here again tomorrow at 5 a.m. Eastern Time for another episode of The Daily Edition. Also, get the news delivered to your podcast app each morning by subscribing to this show. I'm Nancy Johnson. Have a great day.